Value Picks,Buy bombesin peptide

For researchers and scientists seeking high-purity bombesin peptide for sale, understanding the available options, product specifications, and reputable suppliers is crucial. This guide delves into the intricacies of acquiring bombesin, a tetradecapeptide originally isolated from the skin of the fire-bellied toad, Bombina. With its significant biological activity and role as a gastrin-releasing peptide (GRP) analog, bombesin is a valuable tool in various scientific applications, including drug discovery and fundamental biological research.

Understanding Bombesin and its Applications

Bombesin is a 14-amino acid peptide that plays a vital role in the mammalian system, with two known homologs: neuromedin B and gastrin-releasing peptide (GRP). Its biological activity is extensive, influencing hormone release, stimulating pancreatic enzyme secretion, and exhibiting effects in the central nervous system. For instance, bombesin has been observed to suppress feeding in rats and may be involved in regulating fear and anxiety-related behaviors.

In the realm of scientific inquiry, bombesin peptide is utilized in a variety of experimental settings. Researchers often look to buy bombesin peptide for studies involving:

* Receptor Binding Assays: Investigating interactions with bombesin receptor subtypes, such as the bombesin receptor subtype-3 (BRS-3). Compounds like ML-18, a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist, are key tools in these studies.

* Cell Signaling Pathways: Understanding the downstream effects of bombesin activation on cellular processes.

* Peptide Synthesis and Custom Peptide Services: Many suppliers offer custom peptide synthesis, including glycopeptide synthesis, peptide library services, and isotope-labeled peptides, to meet specific research needs.

* Immunohistochemistry and Western Blotting: Utilizing bombesin antibodies, such as Gastrin Releasing Peptide (GRP) / Bombesin Antibody, for detecting and localizing the peptide in biological samples. These antibodies are often generated against synthetic bombesin conjugated to carrier proteins.

* Pharmacological Research: Exploring potential therapeutic applications or understanding the physiological roles of bombesin and its analogs. For example, Litorin, an amphibian bombesin peptide derivative, acts as a bombesin receptor agonist and stimulates smooth muscle contraction.

Where to Find Bombesin Peptide for Sale

When you search for bombesin peptide for sale, you will encounter a range of suppliers offering varying quantities and purities. It's important to note that bombesin is typically sold for scientific research purposes only, and not for human consumption. Some suppliers state a minimum order amount, such as $500.00, to facilitate transactions.

Several reputable biological supply companies offer bombesin in different sizes, often ranging from 0.5 mg to 25 mg or more. Common product listings include:

* Bombesin (1 mg): Available from various sources, with prices around $185 to $240.

* Bombesin (5 mg): Typically priced between $221 and $170, with estimated availability dates sometimes extending into the future.

* Bombesin (10 mg): Often found in the range of $315 to $396.

* Bombesin (25 mg): With prices around $695 to $700.

It is important to check the specific product details, including CAS numbers (e.g., CAS 31362-50-2), molecular weight, and purity, to ensure it meets your experimental requirements. Some vendors may offer biotechnology grade bombesin, ideal for applications such as Western blot and flow cytometry.

When exploring bombesin peptide, you may also come across related products like Bombesin Receptor Modulators, Bombesin Receptor Antagonists, and Bombesin Receptor Agonists. These compounds are invaluable for in-depth investigations into the bombesin signaling pathway.

Important Considerations for Purchasing

* Availability: While many bombesin products are in stock, some may have limited availability or be temporarily withdrawn from sale for commercial reasons, as noted for Bombesin (Cat. No. 1149) by one vendor. Always verify stock status.

* Pricing: Prices can vary significantly between suppliers. Comparing offers for the same quantity and purity is advisable.

* Shipping and Handling: Pay attention to estimated delivery times and any specific storage requirements (e.g., store at 4°C short term, aliquot and store at -20°C long term).

* Custom Synthesis: If standard catalog items do not meet your needs, inquire about custom peptide synthesis services.

* Legal Status: While bombesin peptide is widely available for research, it's always prudent to be aware of regulations regarding peptides in your specific region. For instance, discussions around **peptide treatment